Global health concern on the rising dengue and chikungunya cases in the American regions: Countermeasures and preparedness
Ranjan K. Mohapatra 1, Priyadarshini Bhattacharjee 2, Dhruv N. Desai 3, Venkataramana Kandi 4, Ashish K. Sarangi 5, Snehasish Mishra 6, Ranjit Sah 7,8, Amani Ahmed AL. Ibrahim 9, Ali A. Rabaan 10,11,12, Kudrat E. Zahan 13
1
Department of Chemistry
Government College of Engineering
Keonjhar
Odisha
India
2
Department of Clinical Medicine
Cambridge University Hospitals NHS Foundation Trust
Cambridge
UK
3
Department of Pathobiology
University of Pennsylvania
Philadelphia
Pennsylvania
USA
4
Department of Microbiology
Prathima Institute of Medical Sciences
Karimnagar
Telangana
India
5
Department of Chemistry
Centurion University of Technology and Management
Balangir
Odisha
India
6
School of Biotechnology
KIIT Deemed University
Bhubaneswar
Odisha
India
7
Department of Microbiology
Tribhuvan University Teaching Hospital, Institute of Medicine
Kathmandu
Nepal
8
Department of Clinical Microbiology
Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth
Pune
Maharashtra
India
9
Deparment of Pharmacy
Jubail General Hospital
Jubail
Saudi Arabia
10
Molecular Diagnostic Laboratory
Johns Hopkins Aramco Healthcare
Dhahran
Saudi Arabia
11
Department of Medicine, College of Medicine
Alfaisal University
Riyadh
Saudi Arabia
12
Department of Public Health and Nutrition
The University of Haripur
Haripur
Pakistan
13
Department of Chemistry
Rajshahi University
Rajshahi
Bangladesh
Abstract
Background and Aim Severe morbidity and mortality due to seasonal infectious diseases are common global public health issues. Vector‐borne viral illnesses like dengue and chikungunya overload the healthcare systems leading to critical financial burden to manage them. There is no effective drug or vaccine currently available to control these two diseases.
Methods The review was formulated by incorporating relevant reports on chikungunya and dengue in the Americas regions through a comprehensive search of literature that were available on dedicated scientific publication portals such as PubMed, ScienceDirect, and Web of Science.
Results The strategies of public health administrations to control largely the mosquito vectors during tropical monsoon seem to be effective. Yet, it seems practically impossible to completely eliminate them. The mosquito vector disseminates the virus via transovarian route thereby internalising the virus through generations, a reason behind reappearing and recurring outbreaks. The numerous factors associated with industrialisation, urbanisation, population density, and easy transboundary movements appear to have contributed to the spread of vectors from an endemic region to elsewhere.
Conclusion The article made a state‐of‐affair comprehensive analysis of the rising dengue and chikungunya cases in the tropics, particularly the tropical Americas, as a human health concern, the countermeasures undertaken and the overall preparedness. The viral transmission is a hard situation to tackle as the vector survives in diverse temperature and ecology, is resistant to insecticides, and the unavailability of drugs. Better vector‐control measures and improved understanding of the reemerging arboviral infections could offer an extended reaction time to counter outbreaks, and minimise associated morbidity/mortality.
Keywords: chikungunya; dengue; epidemiology; healthcare; seasonal infection; vector‐borne disease.
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