Chikungunya Archives
Chikungunya
Chikungunya virus virus-like particle vaccine (Vimkunya) induces a rapid and durable antigen-specific CD4+ T cell response
Chikungunya virus (CHIKV), a single-stranded, positive-sense RNA alphavirus, is transmitted to humans by infected Aedes mosquitoes. It poses an emerging threat to public health in Aedes-endemic countries and a growing risk to travelers visiting these countries. Typical acute symptoms include fever, arthralgia,...
Chikungunya
Vaccination against chikungunya - a systematic review on the immunogenicity, tolerability, and safety of the live-attenuated vaccine (LAV) Ixchiq and the virus like particle (VLP) vaccine Vimkunya
Infections with the chikungunya virus are increasingly reported due to many reasons including climate change. Two vaccines against chikungunya have recently been approved in Europe, the live-attenuated vaccine (LAV) Ixchiq and the virus like particle (VLP) vaccine Vimkunya. However, no systematic review...
Chikungunya
Mapping the global risk of chikungunya virus endemicity and autochthonous transmission following importation
Chikungunya virus, emerging as an increasingly significant global health threat, poses significant uncertainty regarding the global risk of its endemicity and autochthonous transmission following importation. In this study, we established a multi-source database spanning 70 years (1953–2023), synthesizing...
Chikungunya
Chikungunya outbreak in Bangladesh (2017): sociodemographic and clinical characteristics of patients from three hotspots
Chikungunya fever (CF) is caused by the chikungunya virus (CHIKV), which is transmitted by Aedes mosquitoes [1]. The disease was first reported in Tanzania, and the name is derived from the ‘Makonde dialect’, which means ‘that which bends up’, about the stooped posture...
Chikungunya
Genomic insights into the re-emergence of chikungunya virus on Runion Island, France, 2024 to 2025.
Chikungunya virus re-emerged on Réunion Island in August 2024, 18 years after a first major outbreak. Analysis of 173 genomes from the current epidemic reveals a monophyletic clade with mutations linked to adaptation to Aedes albopictus mosquitoes, including E1-A226V. Bayesian inference...
