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Interplay between Tetanus, Diphtheria, Acellular Pertussis Vaccination in Pregnancy and Infant Pneumococcal Vaccination in Shaping Infant Pneumococcal Vaccine Serotype Carriage

Published on 21/07/2026 |  Original article (Full-text)  | Eline Van den Bosch et al. | The Journal of infectious diseases. Volume 233(2). 1 min.

Tetanus, diphtheria and acellular pertussis (Tdap) vaccination during pregnancy blunts the infant humoral immune response following primary immunization with pneumococcal conjugate vaccines (PCVs). While this effect typically resolves after the booster dose for most vaccine serotypes, its impact on nasopharyngeal...