Validation of stool and blood analysis compared to Inv A and ttr based direct blood qPCR assay as diagnostic tools for typhoid fever
- Published on 22/07/2025
- Reading time: 5 min.
Elaskary Shymaa A. 1, Badawy Hanem Mohamed 2, Elgendy Doaa S. 3, Abdelmaksoud Amany Mohammed 2, Mostafa Rasha G. 1
1 https://ror.org/05sjrb944 Medical Microbiology and Immunology Department, Faculty of Medicine Menoufia University Shebin al-Kom Egypt
2 https://ror.org/05sjrb944 Clinical Pathology Department, Faculty of Medicine Menoufia University Shebin al-Kom Egypt
3 https://ror.org/05sjrb944 Internal Medicine Department, Faculty of Medicine Menoufia University Shebin al-Kom Egypt
Abstract
Background The development of molecular techniques, such as polymerase chain reaction (qPCR), provides a promising approach for detecting S. enterica due to its rapidity, sensitivity, specificity, and resistance to interference from antibiotics, surpassing the routinely used stool and blood culture methods.
Aim This study aims to compare different stool and blood culturing methods with the direct blood qPCR-based assay of Salmonella Invasion...
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