Epidemiological monitoring for travel medicine specialists


Chikungunya virus circulation is intensifying in French Guiana, with more than 500 laboratory-confirmed cases reported since late January 2026 and a gradual spread of clusters across the territory.
The CDC has issued a Level 2 travel alert for French Guiana, advising travellers to strengthen mosquito bite prevention measures.
In mainland France, no autochthonous cases have been identified to date, but the presence of the tiger mosquito in 81 departments and the rise in imported cases call for increased diagnostic vigilance, even without travel to an epidemic area.
Chikungunya should be considered in patients presenting with sudden-onset fever associated with joint or muscle pain, with mandatory notification required in biologically confirmed cases.
In Africa, the launch of the ACT-CHIK project aims to accelerate the clinical evaluation and local production of a vaccine candidate, in a context of underdiagnosis and growing need for epidemic preparedness.


A new Ebola outbreak was declared in the DRC on May 15, 2026, in Ituri Province, with cases also confirmed in Uganda.
As of May 21, the WHO reported 746 suspected cases and 176 suspected deaths in the DRC, as well as a total of 85 confirmed cases between the DRC and Uganda.
This strain poses a particular challenge, as there is currently no approved vaccine or specific treatment against the Bundibugyo virus. Prevention relies on rapid isolation of cases, contact tracing, protection of healthcare workers, and cross-border coordination.
An outbreak of hantavirus infection has been identified among passengers on the cruise ship MV Hondius, with international coordination initiated following notification to the WHO on May 2, 2026.
This South American strain is unique among hantaviruses because it can be transmitted from person to person through close and prolonged contact; the risk is considered low for the general population.
In France, authorities strengthened monitoring, quarantine, and isolation measures following the return of French nationals, with one confirmed case and 22 contacts initially identified. The WHO considers this alert to be in the process of being resolved.
Classified as a Public Health Emergency of International Concern by the WHO in 2022, monkeypox was recently reclassified as a regional concern.
This containment was made possible by an international vaccination campaign, distributing 5 million doses of MVA-BN and CL16m8 across 16 African countries.
However, local outbreaks are causing concern among European health authorities: primarily Réunion and Mayotte, which have regular links with Madagascar and the Comoros.
A little-known zoonosis, the Nipah virus was discovered in 1998 and is currently experiencing a resurgence in Asia. It was reported during passenger screening at Kathmandu airport.
There is no vaccine for this virus, which causes death in 40 to 70% of cases. Its incubation period (up to 45 days) is a cause for concern among specialists.
In the absence of a vaccine or cure, local authorities recommend avoiding contact with carrier animals (bats, pigs), ensuring that drinking water is clean, and checking the origin of meat.
Fifty million children were offered the typhoid conjugate vaccine (TCV) in Bangladesh in late 2025.
With antimicrobial resistance on the rise, vaccination is becoming a key lever to reduce morbidity and prevent severe disease.
The TCV used in Bangladesh has an estimated effectiveness of 84% in children, and modelling associated with the campaign suggests it could avert up to 8,000 deaths.
Between January 1 and November 2, 2025, 20,412 suspected cases of diphtheria were reported in eight countries in the African Region, including 1,252 deaths (CFR ~6%).
Of these cases, 9,864 (approximately 48.3%) were confirmed; however, confirmation remains low in many countries due to shortages of diagnostic supplies and limited laboratory capacity.