Malaria | Travel Health Xpert

Malaria Archives

Categories: Editorial | Experts Opinions | Congress Highlights

Malaria
Why are iron chelators not as effective as artemisinin in killing malaria parasites?

Published on 25/08/2026 | Original article (Full-text) | Sun, Jun et al. | Parasites & Vectors. Volume 19(1). 1 min.

Artemisinin resistance endangers current artemisinin combination therapy (ACT), necessitating new ACT development. Artemisinin kills malaria parasites by generating free radicals via heme/iron activation, while iron chelators disrupt iron utilization. The combination of these two mechanisms may form...

HTML version PDF version Print abstract

Boolean operators must be written in all capital letters

[space]	Find documents with all the words specified. dopamine homeostasis will get documents with dopamine and homeostasis, found documents must contain the two elements.
OR	Find documents with at least one of the words specified. dopamine OR homeostasis will get documents with word dopamine or homeostasis.
-	The sign - exclude the documents with word or expression specified. dopamine - homeostasis will get the documents with dopamine but without homeostasis. The sign - must be used with others operators.
" "	Find the documents with exactly the expression between the two quotation marks. Example: "symptomatic medication" will find only the documents with "symptomatic medication" in the document.
( )	Brackets are used to group words in a sub expression: (dopamine homeostasis) OR (ergotamine headache)
*	Asterisk is the truncation operator. It can be used as a prefix (with quotation marks) or suffix. *dopa homeo, dopne or "cature"*.

Malaria Archives

MalariaWhy are iron chelators not as effective as artemisinin in killing malaria parasites?

Prof. Éric CAUMES

Prof. Davidson H. HAMER

xxx (MD, PhD)

xxx (MD, PhD)

xxx (MD, PhD)

Malaria
Why are iron chelators not as effective as artemisinin in killing malaria parasites?