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Whole-genome sieve analysis: Identification of protective malaria antigens by leveraging allele-specific vaccine efficacy

Published on 22/04/2025 |  Original article (Full-text)  | Scalsky, Ryan et al. | Vaccine 2025; 50(In progress): 126783 4 min.

Discovery of new protective malaria antigens will enable the development of novel vaccine formulations with potentially higher efficacy. While several high-throughput experimental approaches enable the identification of novel immunogens, none so far has been designed to selectively identify protective...