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Operational challenges and lessons learned from conducting febrile surveillance in a long-term randomized dengue vaccine trial in Latin America and Asia-Pacific

Published on 22/04/2025 |  Original article (Full-text)  | Pfaar, Harald et al. | Travel medicine and infectious disease 2025; AOP:10.1016/j.tmaid.2025.102840 4 min.

In trials, dengue vaccine efficacy evaluation relies on participants presenting with febrile illness/clinically suspected dengue contacting the study site for sample collection and clinical assessment within a short timeframe. Here, we present key considerations to maintain high compliance with the febrile...