Archives News of the month
Dengue Fever
Operational challenges and lessons learned from conducting febrile surveillance in a long-term randomized dengue vaccine trial in Latin America and Asia-Pacific
In trials, dengue vaccine efficacy evaluation relies on participants presenting with febrile illness/clinically suspected dengue contacting the study site for sample collection and clinical assessment within a short timeframe. Here, we present key considerations to maintain high compliance with the febrile...
Dengue Fever
Serotype-specific epidemiological patterns of inapparent versus symptomatic primary dengue virus infections: a 17-year cohort study in Nicaragua
Dengue is the most prevalent mosquito-borne viral disease and a major public health problem worldwide. Most primary infections with the four dengue virus serotypes (DENV1–4) are inapparent; nonetheless, whether the distribution of symptomatic versus inapparent infections by serotype varies remains...
Dengue Fever
Dengue fever ophthalmic manifestations: A review and update
Dengue virus (DENV) is an enveloped RNA virus belonging to the genus Flavivirus of the family Flaviviridae. The viral genome encodes a precursor polypeptide; post‐translational cleavage of this polypeptide by the host cell and the action of virus‐encoded protease results in the...
Dengue Fever
Dengue virus infection and neurological manifestations: an update
Dengue virus is a flavivirus transmitted by the mosquitoes, Aedes aegypti and Aedes albopictus. Dengue infection by all four serotypes (DEN 1 to 4) is endemic globally in regions with tropical and sub-tropical climates, with an estimated 100-400 million infections annually. Among...
Dengue Fever
Dengue
Dengue, caused by four closely related viruses, is a growing global public health concern, with outbreaks capable of overwhelming health-care systems and disrupting economies. Dengue is endemic in more than 100 countries across tropical and subtropical regions worldwide, and the expanding range of the...
