Dengue is the most prevalent mosquito-borne viral disease and a major public health problem worldwide. Most primary infections with the four dengue virus serotypes (DENV1–4) are inapparent; nonetheless, whether the distribution of symptomatic versus inapparent infections by serotype varies remains...
Dengue virus (DENV) is an enveloped RNA virus belonging to the genus Flavivirus of the family Flaviviridae. The viral genome encodes a precursor polypeptide; post‐translational cleavage of this polypeptide by the host cell and the action of virus‐encoded protease results in the...
Dengue virus is a flavivirus transmitted by the mosquitoes, Aedes aegypti and Aedes albopictus. Dengue infection by all four serotypes (DEN 1 to 4) is endemic globally in regions with tropical and sub-tropical climates, with an estimated 100-400 million infections annually. Among...
Dengue, caused by four closely related viruses, is a growing global public health concern, with outbreaks capable of overwhelming health-care systems and disrupting economies. Dengue is endemic in more than 100 countries across tropical and subtropical regions worldwide, and the expanding range of the...
The history of dengue is long, tortured and often muddled; however, our modern understanding of the disease and its epidemiology began only in the late nineteenth century. Australian researchers were at the forefront of our modern understanding of dengue both by careful clinical observations and pioneering...