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 Rabies
Potency, immunogenicity, and efficacy of rabies vaccine: In vitro and in vivo approach

Published on 19/11/2024 |  Original article (Full-text)  | Fahima Akter et al. | Immunity, inflammation and disease 2024; 12(2): 1198 8 min.

The neurotropic rabies virus (RABV), also known as rabies lyssavirus, is the cause of rabies in both people and animals. Rabies can be spread by contact with animal saliva and, less frequently, human saliva. Many mammalian species have been shown to be infected by it in the wild, and in the lab, it has...

 Rabies
Immunogenicity and Safety of a Purified Vero Rabies Vaccine – Serum Free, Compared With Two Licensed Vaccines, in a Simulated Rabies Post-Exposure Regimen in Healthy Adults in France: A Randomized Controlled Phase III Trial

Published on 19/11/2024 |  Original article (Full-text)  | Andrea-Clemencia Pineda-Peña et al. | Clinical infectious diseases 2024; 78(6): 1748-56 4 min.

A next-generation Vero cell rabies vaccine (PVRV-NG2) was developed using the same Pitman–Moore strain as in the licensed purified Vero cell vaccine (PVRV; Verorab®) and the human diploid cell vaccine (HDCV; Imovax Rabies®). This dual-center, modified double-blind, phase III study in France...