Potency, immunogenicity, and efficacy of rabies vaccine: In vitro and in vivo approach
- Published on 19/11/2024
- Reading time: 8 min.
Fahima Akter 1, Md. Shamimuzzaman 2,3
1
Department of Microbiology and Hygiene
Bangladesh Agricultural University
Mymensingh
Bangladesh
2
Department of Microbiology
Jashore University of Science and Technology
Jashore
Bangladesh
3
Directorate General of Drug Administration
Ministry of Health and Family Welfare
Dhaka
Bangladesh
Abstract
Background Rabies, a potentially lethal virus, affects more than 150 countries. Although the rabies vaccine and immunoglobulin have been available since 1908, Bangladesh is new to vaccine manufacturing. We checked the quality of the local manufacturing rabies vaccine for substandard.
Methods The potency and immunogenicity of 20 vaccines were analyzed by three in vivo and in vitro methods from March 2020 to May 2023. Single radial immunodiffusion, fluorescent...
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