Archives News of the month
Zika
Adverse fetal and perinatal outcomes associated with Zika virus infection during pregnancy: an individual participant data meta-analysis
Zika virus (ZIKV) infection during pregnancy is associated with an increased risk of congenital malformations. The prevalence of short and long-term consequences, however, remains uncertain due to heterogeneity across studies. Individual Participant Data Meta-Analysis (IPD-MA) offers an alternative approach...
Zika
Risk of adverse outcomes in offspring with RT-PCR confirmed prenatal Zika virus exposure: an individual participant data meta-analysis of 13 cohorts in the Zika Brazilian Cohorts Consortium
Knowledge regarding the risks associated with Zika virus (ZIKV) infections in pregnancy has relied on individual studies with relatively small sample sizes and variable risk estimates of adverse outcomes, or on surveillance or routinely collected data. Using data from the Zika Brazilian Cohorts Consortium,...
Zika
Immunogenicity and protection of a triple repeat domain III mRNA vaccine against Zika virus
Zika virus (ZIKV) infection is primarily transmitted by mosquitoes and often asymptomatic in most individuals. Infection during pregnancy can lead to severe birth defects such as congenital microcephaly, and currently, there is no approved vaccine for ZIKV. Several studies are investigating the development...
Zika
A prospective, multi‐centric study on the prevalence of dengue, zika and chikungunya in asymptomatic blood donors from different geographical regions of Brazil
Viruses that are transmitted to humans by mosquitoes, ticks and sandflies are grouped under the acronym of arthropoda‐born viruses, as these three vectors belong to the phylum arthropoda. Several members of this group adapted to a life cycle that involves blood meals from mammals and birds, as...
Zika
Neurodevelopmental assessment of normocephalic children born to Zika virus exposed and unexposed pregnant people
Fetal exposure to maternal infections and inflammation may have long-term consequences into early to middle childhood.1 The World Health Organization (WHO) Zika Causality Working Group’s systematic review reported that Zika virus (ZIKV) is a cause of congenital abnormalities, concluding that there...
