
The blood-brain barrier (BBB) protects the brain from pathogenic microorganisms. Neurologic complications from viral infections, including herpes simplex virus, varicella zoster virus, HIV, Japanese encephalitis virus, and SARS-CoV-2, are linked to BBB dysfunction and loss of barrier integrity. Increased...

Vector-borne diseases (VBDs) have been spreading geographically, which is largely attributed to climate change [1–4]. As new areas become suitable for vectors and pathogens, the threat to unexposed populations grows [5]. Japanese encephalitis virus (JEV) is a zoonotic disease transmitted by mosquitoes...

Japanese encephalitis (JE) is an emerging zoonotic disease caused by the Japanese encephalitis virus (JEV), a flavivirus primarily transmitted by mosquitoes of the Culex genus. JE is a significant public health concern, causing around 100,000 cases and 25,000 deaths each year globally [1, 2]....

The Victorian population was largely immunologically naïve to the Japanese encephalitis virus (JEV) before the 2022 outbreak. As most JEV infections are asymptomatic, their prevalence during the outbreak was unknown. The new: We found evidence of JEV infections across northern Victoria, including...

Japanese encephalitis (JE) is a serious health concern in China, with approximately 80% of global infections occurring in China. To develop effective prevention and control strategies, this study explored the epidemiological characteristics of JE in China based on spatiotemporal data, to understand the...